The spicebush (Lindera benzoin) has a fascinating history in the Appalachian region of the United States. Native to eastern North America, including the Appalachian Mountains, this versatile plant has been valued for centuries by indigenous peoples and settlers alike. ABOUT SPICEBUSH 1. Traditional Uses: Native American tribes, such as the Potawatomi, Pamunkey, Cherokee and Iroquois, used spicebush for various purposes. The bark, leaves, and berries were commonly used as ingredients in culinary