Amplified musculoskeletal pain syndromes and Lyme disease “Hallmarks of the diagnosis of Amplified musculoskeletal pain syndrome [AMPS] include increasing pain over time, allodynia, an incongruent affect, disproportional dysfunction, and the absence of other causes.” writes Sherry from Children's Hospital and Regional Medical Center, Seattle in the Journal Rheumatology Supplement. 1 Allodynia is pain due to a stimulus that wouldn't usually cause pain. I have seen Lyme disease patients with AMPS.

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