David Botstein, Gene-Mapping Pioneer, Dies at 83

His method of locating genes in human DNA allowed researchers to find disease-causing genes, and later to map the entire, ...

How a tryptophan-rich allosteric communication network helps activate a major drug target receptor

A multinational research team led by researchers at Institute of Science Tokyo, RIKEN, and the University of Toronto has revealed how a tryptophan-rich allosteric communication network regulates ...

AI model predicts chemical effects on gene expression, speeding drug discovery

Inside a diseased cell, the genes are in chaos. Some are receiving signals to overproduce a protein. Others are reducing ...

Study identifies inflammatory immune pathway driving immunotherapy resistance in bladder cancer

Researchers at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center have discovered a biological pathway that helps explain why some bladder cancers do not respond well ...

Basecamp Research Selects PacBio HiFi Sequencing to Power Trillion Gene Atlas Initiative

PacBio (NASDAQ: PACB), a leading provider of high-quality, long-read sequencing technologies, today announced that Basecamp Research, a frontier AI lab for therapeutic design, has selected PacBio HiFi ...
Frontiers

Modulating the Inflammasome Pathway: Mechanisms and Therapeutic Potential

The innate immune system serves as the first line of defense against pathogens, with inflammasome complexes playing a pivotal role in orchestrating the ...
Frontiers

Genomic and RNA-Based Strategies for Next-Generation Insect Pest Management: From Target Discovery to Functional Control

Advances in genomics and RNA-based technologies are reshaping strategies for insect pest management by enabling the identification and exploitation of ...