Over the past few decades, growing evidence has challenged the belief that inheritance is governed solely by DNA sequences. Scientists now recognize the crucial role of epigenetic inheritance—the ...

A lifetime of rich social connections, from warm parental relationships in childhood to deep community engagement in adulthood, may physically slow the aging process at a cellular level. New research ...

When María Branyas Morera passed away in August 2024, she was 117 years and 168 days old, the planet’s oldest person living at the time. Her life was not only making news—it offered scientists a ...

The global population is ageing rapidly, with the World Health Organization projecting that by 2050, over 2 billion people will be aged 60 or older. This ...

HHMI Janelia Research Campus Senior Group Leader Meng Wang and her team study longevity. They've shown that by overexpressing an enzyme in the lysosomes of the roundworm C. elegans, they can extend ...

Our gut microbes and genes are in constant conversation, shaping each other in ways that affect everything from immunity and inflammation to disease risk, according to new review of scientific ...

Scientists have just taken the most detailed look yet at the biology of a record-breaking human life, profiling a woman who lived to 117 years and 168 days free of cancer, cardiovascular disease and ...

For decades, medicine has been dominated by a “fix-it-when-it-breaks” mentality. A better way forward, what I call healthspan medicine, is proactive, preventive, and personal.

Recent studies suggest that the steady rise in life expectancy observed over the past 200 years has now stagnated. Data indicate that a limit has been reached, and that medical and health care ...

Understanding the mechanisms that drive human aging is one of the great scientific challenges of our time. Traditional measures of aging based solely on ...

Hepatocellular carcinoma (HCC) is the second leading cause of cancer death worldwide, largely due to the limited efficacy of current therapies in advanced stages of the disease. Most cases of HCC ...

In polar bears, dolphins, baboons and more, molecular signatures of aging are changing how conservationists assess population health, resilience and risk ...