Russell Wilson and the Giants are on the road for the second consecutive week against a team with added rest playing its home opener. That's a brutal challenge. But it's even worse because Wilson struggled in Week 1. Dak Prescott did not. The Cowboys will get their first victory here as Prescott plays well.

For consecutive weeks, bettors cashed in on underdogs. As was the case in Week 5, nine of them covered spreads last week.

We don't see the Raiders covering a huge spread in Kansas City, while Jaxson Dart and the Giants could be in for a letdown.

We make picks for all 15 NFL games with levels of confidence ahead of Week 7.

The Arizona Cardinals return home in Week 7. They will face the Green Bay Packers. The Cardinals are big home underdogs to start the week. The Cardinals are 2-4 and have lost four straight games, although they have lost those four games by a total of nine points.