Cardiovascular and cardiometabolic diseases are leading causes of morbidity and mortality worldwide, driven in part by chronic inflammation. Emerging research suggests that the bone marrow ...
Dr Jitesh Neupane discusses his hematoids model and opportunities to study childhood blood disorders and future stem cell therapies.
The American Heart Association makes every effort to avoid any actual or potential conflicts of interest that may arise as a result of an outside relationship or a personal, professional, or business ...
Copyright: © 2025 Published by Elsevier Ltd. Myelodysplastic syndromes are a complex and heterogenous group of clonal myeloid neoplasms, characterised by ineffective ...
Copyright: © 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies. Mitapivat is a potential ...
During human foetal development, the liver is the primary site of blood cell production, but this activity declines in the third trimester and postnatally as haematopoiesis shifts to bone marrow. In ...
You et al. present an important study that applied a high-resolution transposon-based barcoding system to show the clonal contribution of hematopoietic stem and progenitor cells during aging, after ...
RECENT research has uncovered key insights into the genetic mechanisms driving age-related clonal haematopoiesis (CH), a condition linked to inflammatory cardiovascular disease and myeloid ...
Hyperthermic Intraperitoneal Chemotherapy in Platinum-Sensitive Recurrent Ovarian Cancer: A Randomized Trial on Survival Evaluation (HORSE; MITO-18) Clonal hematopoiesis (CH) has been associated with ...
ABSTRACT: There is a considerable demand but limited supply for hematopoietic stem cells (HSCs) in clinics. To meet clinical needs of HSCs, new efforts focus on de novo HSCs generation from ...
A RECENT study examining long-term effects of allogeneic hematopoietic cell transplantation (HCT) has provided new insights into the behaviour of clonal haematopoiesis (CH) following transplantation.