BRCA gene mutations can significantly raise a woman’s risk of breast and ovarian cancer. Know how hereditary cancer risk works and why genetic testing and early screening matter.

A clustered family history of breast, ovarian, and colon cancers appropriately triggered germline testing, with BRCA1 mutation status informing individualized risk stratification and counseling.

Breast cancer is a prevalent cancer in women across the globe. Although a majority of the instances are isolated, hereditary cases associated with genetic mutations are found in 5-10 percent. Of these ...

We talked to experts about new research connecting mutations in BRCA genes to other forms of cancer besides breast and ovarian. If you typically think of BRCA gene mutations along with certain breast ...

(WASHINGTON, June 13, 2025) – Women with breast cancer who were also carriers of the BRCA1 or BRCA2 mutation and received textured breast implants as part of their reconstructive surgery after ...

Risk assessments for cancers related to BRCA mutations could save lives. Annually, about 247,200 cases of breast cancer are diagnosed in the U.S. and nearly 42,000 people die each year from breast ...

In young BRCA carriers who survived breast cancer, assisted reproductive techniques (ART) did not increase the risk of disease recurrence or adversely affect pregnancy outcomes, findings of an ...

Lynparza significantly improves iDFS, DDFS, and OS in BRCA1/2 mutation-positive, HER2-negative high-risk breast cancer patients. The trial's six-year analysis shows consistent benefits across all ...

Of the more than 3 million people with breast cancer in the United Stated, about 10 percent carry an inherited mutation in their BRCA1 gene. In health, the gene is responsible for suppressing tumors.

Patients with BRCA-mutant breast cancer had a significantly higher risk of breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL), a large cohort study showed. BRCA1/2 mutations conferred ...

Breast-conserving therapy for BRCA1/2 mutation carriers has higher risks of future breast cancers than the general population, but most patients avoid another cancer event, and many remain bilateral ...

For 12 years, the father of three believed he was doing everything possible to stay ahead of the disease by never missing an annual mammogram. However, in December 2025, on his 53rd birthday, Johnson ...