Process development, facility management, and large-scale manufacturing were among the key issues discussed at the “Sixth European Biotechnology Symposium,” which was sponsored by Genetic Engineering ...
Over two-thirds of biopharmaceutical manufacturers now report that their facility is experiencing capacity bottlenecks due to downstream processing. A number of factors continue to converge to create ...
Downstream processing encompasses the sequence of operations required to isolate, purify and formulate a biopharmaceutical product from crude biological feedstock. Following cell culture or ...
Over the last few years, the number of recombinant pharmaceutical products that have entered the regulatory fray to gain approval for marketing has grown rapidly, and is now in the hundreds. As ...
Based on 2025 statistics from the World Economic Forum and International Energy Agency, China has built mature refining capacity across nearly all core global critical minerals. Split by industry ...
Downstream processing encompasses the suite of separation, purification and formulation steps required to convert fermentation broths or other bioreactor outputs into high-purity bio-based chemicals.
In this brochure, Thermo Scientific takes a closer look at how integrated hot-melt extrusion (HME) workflows, paired with flexible downstream processing technologies from Thermo Fisher Scientific, can ...
Upstream titers of 3–5 g/L, and up to 10–13 g/L, are outpacing downstream capacity, creating chromatography, filtration, and UF/DF throughput bottlenecks that elevate cost and delay timelines. Complex ...
The two main fixation formats used by researchers are formalin fixation followed by paraffin embedding (FFPE) or snap-frozen in liquid nitrogen (referred to as Fresh Frozen or FF). There is less of a ...
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