IS110 transposons are a large, diverse family of bacterial insertion sequences (IS elements)—small, mobile DNA elements that ...

DNA is the blueprint of the human body. However, tens of thousands of DNA lesions occur in our bodies every day. In ...

Transposons, so-called jumping genes, are a threat to genomes, so plants work hard to prevent them from mobilizing and re-inserting into the genome. Spirodela polyrhiza, the most ancient member of the ...

Researchers have captured the first atomic structures of human SMUG1, an enzyme that helps cells repair damaged DNA. The ...

In a study published in Cell, a research team led by ZHANG Yong'e and WANG Haoyi from the Institute of Zoology of the Chinese Academy of Sciences has characterized the diversity of DNA transposons and ...

Transposons, DNA sequences that can self-replicate and move (jump) throughout the genome, are widespread and can affect cell ...

Cornell researchers have found that a new DNA sequencing technology can be used to study how transposons move within and bind to the genome. Transposons play critical roles in immune response, ...

Scientists have created a live-cell DNA sensor that reveals how damage appears and disappears inside living cells, capturing the entire repair sequence as it unfolds. Instead of freezing cells at ...

Transposons are critical drivers of bacterial evolution that have been studied for many decades and have been the subject of Nobel Prize winning research. Now, researchers from Cornell University have ...

DNA repair is essential for the maintenance of genomic stability and its failure can lead to human disease. Various DNA repair systems exist, such as base excision repair, nucleotide excision repair, ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...