A large-scale genetic analysis has identified 36 genes carrying rare mutations that substantially increase the likelihood of developing obsessive-compulsive disorder, chronic tic disorders, or both.

New research in mice reveals how reducing food intake can influence DNA across the genome, potentially pointing toward new ...

A rare mutation in a gene called FN1 may help explain why some people with the strongest common genetic risk for Alzheimer’s ...

Researchers in a Mayo Clinic-led study have shown how to detect a broad range of DNA mutations in noncancerous human tissues ...

Cancers can develop through epigenetic pathways even without driver gene mutations (DGMs), according to a study from Science ...

Researchers from the University of California San Diego and collaborators have identified a previously overlooked pattern of DNA mutations in colorectal cancer. Scientists use these patterns, known as ...

Every cell carries a molecular record of time. As DNA is copied, repaired and exposed to damage, mutations gradually accumulate — most harmless, some potentially consequential. A new Cell study found ...

A new narrative review finds that germline mutations underlie up to 20 to 35 percent of pediatric aplastic anemia and MDS ...

A retrospective review of 88 patients with advanced Philadelphia chromosome-negative myeloproliferative neoplasms identifies age, white blood cell count, prior myelofibrosis, adverse karyotype, and ...

In simple terms: a mutation is a stable change in genetic sequence that can be copied when cells or viruses replicate. Most mutations have no detectable effect, some contribute to disease, and a small ...

Most lethal mutations in wild fruit flies are driven by newly transferred jumping genes, not small DNA errors, according to a new study from Duke University. The findings, published in PLOS Biology, ...