Cytokines are essential mediators of immune functions and regulate many other biological processes, ranging from fetal development to ageing. Dysregulation of cytokine responses can substantially ...

Cells have sophisticated methods of sensing stimuli and communicating with nearby cells in response to these stimuli. For example, macrophages can sense environmental stimuli—tissue damage, foreign ...

Glioma associated macrophages/microglia (GAMs) play an important role in glioblastoma (GBM) progression, due to their massive recruitment to the tumor site and polarization to a tumor promoting ...

Cytokines contribute to the antitumor response through several key pathways and interactions with different immune cells. These include the following: (a) Natural killer (NK) cells: Cytokines such as ...

Cleveland Clinic's Lerner Research Institute was awarded a five-year $12 million grant by the National Cancer Institute, part of the National Institutes of Health, to define how cytokines - proteins ...

Cancer immunotherapy has advanced significantly in recent years, dramatically improving patient prognosis and survival. The majority of cancer immunotherapy research currently focuses on the first T ...

Researchers at Indiana University School of Medicine Department of Microbiology and Immunology have made an important new discovery about how a particular molecule could improve lung function for ...

The Interleukin-1 Receptor-Like 2 (IL-1RL2) cytokine can promote inflammatory diseases and have a role in controlling infection. The receptor can recognize multiple agonists and has been implicated in ...

The job of your immune system is to protect your body from harmful foreign substances and keep you healthy. But sometimes your immune system does your body more harm than good. A cytokine storm occurs ...

Cytokines and their kin, alternatively called interleukins, growth factors, interferons, necrosis factors, and others, are soluble messengers responsible for communication between nearby cells, ...

A collaborative research team has successfully developed designer enzymes that exhibit both intrinsic and extrinsic functions by transplanting a synthetic trinuclear zinc center into a human cytokine.

Psoriasis causes your body to make new skin cells too quickly. These cells tend to pile up and form spots, bumps, and thick scaly patches called plaques that can be uncomfortable. Scientists think ...