A new study investigating neuroinflammation in the ventral tegmental area (VTA) of the brain, a small, midbrain dopaminergic region, has found that acute and chronic depression are associated with ...

Chronic stress can damage the gut’s protective lining, triggering inflammation that may worsen depression. New research shows that stress lowers levels of a protein called Reelin, which plays a key ...

Patients with chronic depression can be differentiated from those with episodic depression according to their levels of cognitive–behavioural and emotional avoidance, study findings suggest.

Chronic pain—or pain that lasts at least three months—is closely intertwined with depression. Individuals living with pain's persistent symptoms may be up to four times more likely to experience ...

Chronic sorrow has been described in the caregivers of individuals with myelomeningocele, multiple sclerosis, Parkinson's disease, cancer, and premature infants. Most studies have reported small ...

In an analysis of 79 studies totaling almost 23,000 youth, the prevalence of anxiety was 34.6% in those with chronic pain, and the prevalence of depression was 12.2%, Joanne Dudeney, PhD, of the ...

The investigators identified a total of 376 relevant studies from 50 countries, including 347,468 individuals (70% of whom were female) with chronic pain. The pooled prevalence rates for depression ...

Depression and anxiety affect approximately 40% of adults with chronic pain, according to a massive new systematic review and meta-analysis published in JAMA Network Open. The comprehensive study ...

Young people with chronic pain are three times more likely than their peers to also have clinical anxiety or depression, a new review has found. Led by researchers at Macquarie University, the study ...

Four in ten adults with chronic pain experience clinically significant depression and anxiety, reported a new systematic review and meta-analysis published in JAMA Network Open. "Right now, we have ...

People who live with chronic pain also often experience psychiatric disorders, like depression or anxiety, complicating the treatment of both conditions. Although many of the same brain regions are ...