A new University of Utah-led study has discovered the mechanism behind a decades-old evolutionary mystery-how "selfish chromosomes" cheat the rules of genetic inheritance.

Loss of the Y chromosome in aging men is widespread and increasingly linked to serious diseases, challenging assumptions that ...

When closely related species mate, their offspring sometimes survive but cannot reproduce. This pattern often affects males ...

For sexual reproduction to yield healthy offspring, newly generated oocytes—immature egg cells—must receive the correct amount of DNA after cell division. This process of segregating chromosomes ...

Researchers created artificial kinetochore structures that reduce chromosome separation errors during meiosis in aging egg cells. By lowering microtubule pulling force, the approach helped maintain ...

The Y chromosome is among the smallest in the human body and carries the fewest genes. Researchers are paying renewed attention to its role in cancer—specifically, what happens when it vanishes.

Most mammals, including humans, have two sex chromosomes, X and Y. One sex chromosome is usually inherited from each parent, and they pair up as either XX or XY in every cell of the body. People with ...

In a milestone achievement, a whole chromosome has been created from scratch by scientists for the first time ever. The tRNA Neochromosome is a man-made chromosome of the common baker's yeast ...

Yale scientists have discovered a new potential treatment avenue to fight cancer. Using CRISPR gene-editing, the team eliminated extra chromosomes from cancer cells and found that they could no longer ...

New research reveals that ancient interbreeding between humans and Neanderthals shaped our modern human DNA - especially on the X chromosome.

Triploidy is a condition that affects 1% to 3% of pregnancies. It’s when a developing baby has an extra set of chromosomes, the thread-like structures that carry DNA. A triploidy pregnancy usually ...