San Francisco 49ers RB Christian McCaffrey bursts through the defense for a 41-yard run against the Chicago Bears.

San Francisco 49ers running back Christian McCaffrey follows two perfect blocks en route to a 5-yard touchdown run.

San Francisco 49ers running back Christian McCaffrey can add another historic mark to his legacy against the Philadelphia ...

A meeting featuring two of the NFL's best in Christian McCaffrey and Jonathan Taylor will close Week 16 as the 49ers and ...

The 49ers' star running back reflected on his missed chance and took full flame for his mistake late in Week 18.

The 2025 fantasy football is in the books, and boy was it a whopper!  We saw some really crazy stuff, such as Lamar Jackson ...

A summary of the best fantasy performances, biggest storylines, surprises and disappointments, along with the usual dose of ...

The San Francisco 49ers just didn’t have the horses to hang with the Seattle Seahawks in their Week 18 matchup.

NFL 1,000-1,000 yards club: How Christian McCaffrey's rare receiving, rushing feats compare to history originally appeared on ...

The 49ers have a deserved reputation as a prolific offensive team, but there are elements the Eagles can exploit on Sunday.

McCaffrey (back) doesn't have a designation for Saturday's game against the Seahawks, Nick Wagoner of ESPN.com reports.