A study by Dorothy P. Schafer, Ph.D., and Travis E. Faust, Ph.D., at UMass Chan Medical School, explains how two different cell types in the brain—astrocytes and microglia—communicate in response to ...

The human brain can do many amazing things, but self-repair is not one of its repertoire of abilities. Once neurons die—from trauma, stroke, or disease—they rarely grow back. Scientists have been ...

Healing from any injury involves a delicate balance between scarring and inflammation — two processes that can wreak havoc as well as make repairs. When the injury is to the brain, the balance is that ...

Microglia are the silent guardians of the brain. They hunt down pathogens, clean up toxic protein clumps, and even shape the brain’s wiring. They’re also robust. Neurons can’t divide to generate new ...

Scientists in Japan have created powerful new vitamin K-based compounds that may help the brain regenerate lost neurons — a breakthrough that could one day change how diseases like Alzheimer’s and ...

Cells long thought to play a secondary role in brain function build their own far-reaching connections, according to a new study in mice. These pathways appear to connect distant regions in ways that ...

The new generation of Alzheimer's disease drugs—the first proven to change the course of the disease—typically extend independent living for patients by 10 months. Called monoclonal antibodies, they ...

The tiny chips hitch a ride on immune cells to target inflammation in the brain. Scientists hope to kick off clinical trials within three years. From restoring movement and speech in people with ...

Delivering a connection-building protein to star-shaped cells in the brain could reverse changes to neural circuits seen in Down syndrome, according to new research my colleagues and I published in ...

Scientists have developed a promising new approach to treating Alzheimer’s disease by turning ordinary brain cells into powerful plaque-clearing machines. Instead of requiring frequent antibody ...