The proteins of the Bcl-2 family are key players in the mitochondrial pathway of apoptosis. They form a complex interaction network that determines the permeabilization of the mitochondrial outer ...
Bax is a member of the Bcl-2 family that, together with Bak, is required for permeabilisation of the outer mitochondrial membrane (OMM). Bax differs from Bak in that it is predominantly cytosolic in ...
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