One of the biggest quests in biology is understanding how every cell in an animal’s body carries an identical genome yet still gives rise to a kaleidoscope of different cell types and tissues. A ...

Animal cell types are defined by differential access to genomic information—a process orchestrated by the combinatorial activity of transcription factors that bind to cis-regulatory elements (CREs) to ...

A recent study by Ruibao Li and Jennah Dharamshi published in Nature may help us understand the beginnings of animal evolution billions of years ago. These findings are the result of a collaboration ...

Full-body defense does not always look the way textbooks say it should. In planarian flatworms, a newly identified cell type ...

Animals, from worms and sponges to jellyfish and whales, contain anywhere from a few thousand to tens of trillions of nearly genetically identical cells. Depending on the organism, these cells arrange ...

Five animal species can rebuild organs, limbs, and tissues that most vertebrates permanently lose after injury. Planarians regrow entire bodies from tiny fragments using adult pluripotent stem cells ...

In recent years, calcium imaging has emerged as a powerful tool for dissecting neural circuit function in rodents. This technique measures real-time changes in cellular calcium dynamics as a proxy for ...

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