Nature

A targeted next-generation sequencing panel for identification of clinically relevant mutation profiles in solid tumours

Classic histo-morphological diagnosis by immunohistochemistry and fluorescence in-situ hybridization is undoubtedly the gold standard in pathology. However, it is often necessary to characterize a ...
The Scientist

Ultima Genomics Introduces the Next Generation of Sequencing at Scale with the Launch of the UG200™ Series and Next Generation Solaris 2.0 Workflows

Ultima Genomics, Inc., a developer of ultra-high-throughput sequencing systems, continues its mission to enable sequencing at scale with the unveiling of the UG200 Series and next generation Solaris 2 ...
GEN

Next-Generation Size Selection for Optimized Long-Read Sequencing Workflow

Whole genome analysis plays a critical role in the development of life-saving diagnostics, therapeutics, and vaccines, with growing interest in noncoding regions and Whole genome analysis plays a ...
Miami University

Miami University acquires new third-generation DNA sequencing technology, first in Midwest

Miami University’s Center for Bioinformatics and Functional Genomics (CBFG) has become one of the first institutions in the region to acquire the PacBio VEGA Benchtop System — a cutting-edge DNA ...
GEN

The Throughput Paradox: Why Next-Generation Sequencing Bottlenecks Persist Beyond the Sequencer

The landscape of next-generation sequencing (NGS) continues to be defined by astonishing technological progress. We continue to witness sequencer throughput expansion with systems like the Illumina ...
ascopubs.org

Plasma-based next generation sequencing in advanced non-small cell lung cancer (NSCLC): Significance in diagnosis and treatment.

Evaluating the Khorana score in advanced EGFR-mutated NSCLC patients receiving first-line osimertinib. Nimotuzumab plus chemotherapy in the posterior-line treatment for lung adenocarcinoma with ...
RAPS

FDA drafts guidance on using next-generation sequencing to assess gene therapy safety

The US Food and Drug Administration (FDA) has released draft guidance on how sponsors can utilize next-generation sequencing (NGS) methods in nonclinical studies to assess the safety risks associated ...
Nature

Direct high-throughput deconvolution of non-canonical bases via nanopore sequencing and bootstrapped learning

Synthetic xeno-nucleic acids (XNAs) consist of unnatural bases (UBs) beyond the canonical A, T, C, G, and U found in naturally occurring DNA and RNA. Such non-canonical bases (NCBs) expand the ...