Both the Los Angeles Rams and San Francisco 49ers sport 3-1 records entering Week 5, which they'll kick off on "Thursday Night Football." Yet only one is operating with momentum. The Rams just took care of business against an upstart contender in the Indianapolis Colts,

The Miami Dolphins appear set to be sellers at the 2025 NFL trade deadline, and they have a player the San Francisco 49ers and Cleveland Browns could want.

With a showdown with a division rival coming up on a short week, the San Francisco 49ers are staring down a potentially uncomfortable situation with Brock Purdy, their franchise quarterback managing a toe injury.

The San Francisco 49ers and Los Angeles Rams will meet at SoFi Stadium on Thursday. Here's what fantasy owners should do with their 49ers in Week 5.

The Los Angeles Rams are tasked with stopping one of the best running backs in the NFL for a third straight week

In the studio: TNF studio presence Andrew Whitworth blocked for Stafford in the Rams’ 2021 Super Bowl campaign. Fellow analyst Richard Sherman was born in Compton, went to Stanford and played for the 49ers. A third member of the team, Tony Gonzalez, hails from Torrance (southwestern Los Angeles County).

To replace those departed contributors, the 49ers focused on the 2025 NFL draft and rebuilding their defense. It was a roster reimagining following a similar blueprint of the 2023 Los Angeles Rams and 2024 Buffalo Bills, both teams that Lynch says his staff spent time studying before the offseason began.

San Francisco 49ers tight end George Kittle has been on injured reserve since Week 2, which means he's eligible to be activated in Week 6. But will that happen? Here's what we know.